Title
Feature and Classifier Selection for Automatic Classification of Lesions in Dynamic Contrast-Enhanced MRI of the Breast
Abstract
The clinical interpretation of breast MRI remains largely subjective, and the reported findings qualitative. Although the sensitivity of the method for detecting breast cancer is high, its specificity is poor. Computerised interpretation offers the possibility of improving specificity through objective quantitative measurement. This paper reviews the plethora of such features that have been proposed and presents a preliminary study of the most discriminatory features for dynamic contrast-enhanced MRI of the breast. In particular the results of a feature/classifier selection experiment are presented based on 20 lesions (10 malignant and 10 benign) from 20 routine clinical breast MRI examinations. Each lesion was segmented manually by a clinical radiographer and its diagnostic status confirmed by cytopathology or histopathology. The results show that textural and kinetic, rather than morphometric, features are the most important for lesion classification. They also show that the SVM classifier with sigmoid kernel performs better than other well-known classifiers: Fisher's linear discriminant function, Bayes linear classifier, logistic regression, and SVM with other kernels (distance, exponential, and radial).
Year
DOI
Venue
2009
10.1109/DICTA.2009.29
Melbourne, VIC
Keywords
Field
DocType
automatic classification,breast mri,dynamic contrast-enhanced mri,routine clinical breast,svm classifier,breast cancer,classifier selection experiment,classifier selection,mri examination,bayes linear classifier,clinical radiographer,clinical interpretation,image classification,classification,dynamic contrast enhanced mri,magnetic resonance imaging,kinetics,image segmentation,support vector machines,cancer,pattern recognition,features,logistic regression,kinetic theory,feature extraction,entropy,mri
Breast cancer,Computer science,Breast MRI,Artificial intelligence,Classifier (linguistics),Computer vision,Pattern recognition,Support vector machine,Feature extraction,Linear discriminant analysis,Linear classifier,Dynamic contrast-enhanced MRI,Machine learning
Conference
ISBN
Citations 
PageRank 
978-0-7695-3866-2
3
0.44
References 
Authors
6
5
Name
Order
Citations
PageRank
Yaniv Gal1356.32
Andrew Mehnert214014.07
Andrew P. Bradley32087195.95
Dominic Kennedy4232.04
Stuart Crozier513014.02