Abstract | ||
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An analytical model is proposed to calculate the initial infusion of a microneedle array driven by a micropump. By assuming the initial infusion of each microneedle undergoes a spherical expansion, the model is able to calculate the time-varying expansion radius, as well as the flow rate and infusion pressure, provided that the material properties and the microneedle system parameters are known. For a selected piezoelectric micropump, our results show that the expansion under the skin stops and the flow rate drops to zero in a short time. We also found that the initial flow characteristics are strongly influenced by the material properties of the skin and parameters of the drug deliver system. |
Year | DOI | Venue |
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2011 | 10.1109/BMEI.2011.6098420 | BMEI |
Keywords | Field | DocType |
spherical expansion,microneedle array,material properties,time-varying expansion radius,biomems,initial fluid infusion,microneedle,microneedle drug delivery system,piezoelectric micropump,flow rate,micropumps,biomedical equipment,micropump,analytical model,piezoelectric devices,drug delivery systems,component,skin,mathematical model,solids | Biomedical engineering,Computer vision,Nanotechnology,Computer science,Flow (psychology),Biomedical equipment,Micropump,Artificial intelligence,Material properties,Drug delivery,Volumetric flow rate,Piezoelectricity | Conference |
Volume | Issue | ISBN |
2 | null | 978-1-4244-9351-7 |
Citations | PageRank | References |
0 | 0.34 | 1 |
Authors | ||
3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Fenglei Yang | 1 | 8 | 2.50 |
Kai Chen | 2 | 0 | 0.34 |
Zhigang Feng | 3 | 11 | 2.86 |