Title
Assist-As-Needed Training Paradigms For Robotic Rehabilitation Of Spinal Cord Injuries
Abstract
This paper introduces a new "assist-as-needed" (AAN) training paradigm for rehabilitation of spinal cord injuries via robotic training devices. In the pilot study reported in this paper, nine female adult Swiss-Webster mice were divided into three groups, each experiencing a different robotic training control strategy: a fixed training trajectory (Fixed Group, A), an AAN training method without interlimb coordination (Band Group, B), and an AAN training method with bilateral hindlimb coordination (Window Group, C). Fourteen days after complete transection at the mid-thoracic level, the mice were robotically trained to step in the presence of an acutely administered serotonin agonist, quipazine, for a period of six weeks. The mice that received AAN training (Groups B and C) show higher levels of recovery than Group A mice, as measured by the number, consistency, and periodicity of steps realized during testing sessions. Group C displays a higher incidence of alternating stepping than Group B. These results indicate that this training approach may be more effective than fixed trajectory paradigms in promoting robust post-injury stepping behavior. Furthermore, the constraint of interlimb coordination appears to be an important contribution to successful training.
Year
DOI
Venue
2006
10.1109/ROBOT.2006.1642237
2006 IEEE INTERNATIONAL CONFERENCE ON ROBOTICS AND AUTOMATION (ICRA), VOLS 1-10
Keywords
Field
DocType
assist-as-needed, rehabilitative robotics, spinal cord injury
Spinal cord,Spinal cord injury,Rehabilitation,Medical robotics,Control engineering,Quipazine,Physical medicine and rehabilitation,Rehabilitation robotics,Engineering
Conference
Volume
Issue
ISSN
2006
1
1050-4729
Citations 
PageRank 
References 
6
0.77
0
Authors
5
Name
Order
Citations
PageRank
Cai Li1786.80
Andy J. Fong260.77
Yongqiang Liang3111.36
Burdick, J.W.42988516.87
V. Reggie Edgerton5336.76