Title
A study on validity of cortical alpha connectivity for schizophrenia.
Abstract
Abnormalities in schizophrenia are thought to be associated with functional disconnections between different brain regions. Most previous studies on schizophrenia have considered high-band connectivity in preference to the Alpha band, as there has been some uncertainty correlating the latter to the condition. In this paper we attempt to clarify this correlation using an Electroencephalogram (EEG) analysis of the Alpha band from schizophrenic patients. Global, regional Omega and dimensional complexity and local Omega complexity differentials (LCD) of single channel are calculated using 16 channels of resting EEG data from 31 adult patients with schizophrenia and 31 age/sex matched control subjects. It was found that, compared to the controls, anterior alpha Omega and dimensional complexity are higher in schizophrenia patients (p<0.05) with the single channel LCD also increasing at FP1, FP2, F7 and F8 electrodes. Furthermore, higher left hemisphere dimensional complexity and LCD at T3 point was also found. The results suggest there is lower connectivity in the pre-frontal and left temporal regions with respect to the alpha band in schizophrenia patients.
Year
DOI
Venue
2013
10.1109/EMBC.2013.6610243
EMBC
Keywords
Field
DocType
medical disorders,brain regions,fp1 electrodes,electroencephalogram,biomedical electrodes,electroencephalography,local omega complexity differentials,t3 point,f7 electrodes,regional omega complexity,schizophrenic patients,left hemisphere dimensional complexity,alpha band,fp2 electrodes,global complexity,prefrontal region,f8 electrodes,left temporal region,resting eeg data,anterior alpha omega,cortical alpha connectivity,single channel lcd,information processing,electrodes,psychiatry
Alpha (ethology),Neuroscience,Temporal Regions,Lateralization of brain function,Psychology,Correlation,Omega,Eeg data,Schizophrenia,Electroencephalography
Conference
Volume
Issue
ISSN
2013
null
1557-170X
Citations 
PageRank 
References 
1
0.36
1
Authors
9
Name
Order
Citations
PageRank
Hong Peng18111.42
Bin Hu2778107.21
Lanlan Li3182.36
Martyn Ratcliffe4565.12
Jingwei Zhai510.36
Qinglin Zhao615826.30
Qiuxia Shi7212.09
Yunpeng Li857845.91
Quanying Liu9434.67