Title
Effects Of Stenosis On The Porcine Left Anterior Descending Arterial Tree
Abstract
In this study, hemodynamics in the normal and diseased left anterior descending (LAD) arterial trees were compared to estimate the effects of stenosis on the flow rate distribution, detailed flow field and wall shear stress (WSS) distributions on both transient and steady flow conditions. The anatomical model was reconstructed from computed tomography (CT) images of a normal porcine heart. Stenosis was imposed at the trunk of LAD tree with different area stenosis ratios (25%, 50%, 75% and 90%) to study the effect of stenosis. It has been found that the steady-state simulation is competent to demonstrate the prominent flow features of transit flow. Only significant stenosis altered the flow rate considerably, and its effects diminished at the downstream bifurcations. Based on the WSS distribution, non-significant stenosis potentially led to the development of atherosclerosis near the ostium of the downstream side branch and significant stenosis might promote atherosclerosis in its wake.
Year
DOI
Venue
2013
10.1109/EMBC.2013.6610389
2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
Keywords
Field
DocType
solid modeling,computational fluid dynamics,cardiology,hemodynamics,physiology,haemodynamics,heart,image reconstruction,boundary conditions
Hemodynamics,Internal medicine,Computer science,Shear stress,Cardiology,Stenosis,Ostium,Computed tomography,Trunk,Arterial tree
Conference
Volume
Issue
ISSN
2013
null
1557-170X
Citations 
PageRank 
References 
0
0.34
1
Authors
7
Name
Order
Citations
PageRank
Liang Zhong14312.20
Boyang Su2134.91
Junmei Zhang3259.11
Yunlong Huo421.13
Hwa Liang Leo500.34
Ghassan S. Kassab631.53
Ru-San Tan723922.37