Title
Privacy-Preserving Patient-Centric Clinical Decision Support System on Naive Bayesian Classification
Abstract
Clinical decision support system, which uses advanced data mining techniques to help clinician make proper decisions, has received considerable attention recently. The advantages of clinical decision support system include not only improving diagnosis accuracy but also reducing diagnosis time. Specifically, with large amounts of clinical data generated everyday, na¨ıve Bayesian classification can be utilized to excavate valuable information to improve clinical decision support system. Although clinical decision support system is quite promising, the flourish of the system still faces many challenges including information security and privacy concerns. In this paper, we propose a new privacy-preserving patient-centric clinical decision support system, which helps clinician complementary to diagnose the risk of patients’ disease in a privacy-preserving way. In the proposed system, the past patients’ historical data are stored in cloud and can be used to train the naïve Bayesian classifier without leaking any individual patient medical data, and then the trained classifier can be applied to compute the disease risk for new coming patients and also allow these patients to retrieve the top-k disease names according to their own preferences. Specifically, to protect the privacy of past patients’ historical data, a new cryptographic tool called additive homomorphic proxy aggregation scheme is designed. Moreover, to leverage the leakage of naïve Bayesian classifier, we introduce a privacy-preserving top-k disease names retrieval protocol in our system. Detailed privacy analysis ensures that patient’s information is private and will not be leaked out during the disease diagnosis phase. In addition, performance evaluation via extensive simulations also demonstrates that our system can efficiently calculate patient’s disease risk with high accuracy in a privacy-preserving way.
Year
DOI
Venue
2016
10.1109/JBHI.2015.2407157
IEEE J. Biomedical and Health Informatics
Keywords
DocType
Volume
clinical decision,patient-centric,privacy- preserving,support system,naïve bayesian classifier
Journal
PP
Issue
ISSN
Citations 
99
2168-2194
45
PageRank 
References 
Authors
1.29
19
5
Name
Order
Citations
PageRank
Ximeng Liu126412.54
Rongxing Lu25091301.87
Jianfeng Ma31336155.62
Le Chen425210.62
Baodong Qin519019.40