Paper Info
Title
Fragmental Frequency Analysis Method to Estimate Electrical Cell Parameters From Bioimpedance Study
Abstract
This paper introduces an alternate approach utilizing the fragmental frequency analysis method for analyzing bioimpedance data to estimate electrical cell parameters. Impedance of cervical cancer cells (HeLa) in phosphate buffer saline media is measured using an electric cell-substrate impedance sensing (ECIS) device and impedance analyzer. The measured impedance data were visualized by modeling an equivalent electrical circuit of the system considering the dominancy of individual parameters of the ECIS system and analyzed in different frequency zones. The present approach eliminates the convergence inaccuracy in fitting the experimental impedance data with fitting software arising due to invalid initial conditions, and a large number of data points. This method provides high-frequency characterization, modeling of ECIS system, knowledge of effect of ECIS model parameters with frequency, and an alternate way to calculate model parameters.
Year
DOI
Venue
2014
10.1109/TIM.2014.2303553
IEEE T. Instrumentation and Measurement
Keywords
DocType
Volume
gynaecology,ECIS,electric cell-substrate impedance sensing device,fitting software,cellular biophysics,fragmental frequency analysis,fragmental frequency analysis method,Bode??Nyquist plot,impedance analyzer,electrical cell parameters,Bioimpedance,impedance spectrum,electric impedance measurement,bioimpedance study,convergence,cancer,bioelectric phenomena,equivalent electrical circuit modeling,phosphate buffer saline media,Bode--Nyquist plot,data points,HeLa,cervical cancer cells,convergence inaccuracy
Journal
63
Issue
ISSN
Citations 
8
0018-9456
0
PageRank 
References 
Authors
0.34
3
5
Name
Order
Citations
PageRank
Debanjan Das103.38
Farhan Ahmad Kamil200.34
Snehil Agrawal300.34
K. Biswas415925.99
S. Das5104.69