Name
Title | ||
|---|---|---|
The influence of intraluminal thrombus on noninvasive abdominal aortic aneurysm wall distensibility measurement. |
Abstract | ||
|---|---|---|
Abdominal aortic aneurysm wall distensibility can be estimated by measuring pulse pressure and the corresponding sac volume change, which can be obtained by measuring wall displacement. This approach, however, may introduce error if the role of thrombus in assisting the wall in bearing the pulse pressure loading is neglected. Our aim was to introduce a methodology for evaluating and potentially correcting this error in estimating distensibility. Electrocardiogram-gated computed tomography images of eleven patients were obtained, and the volume change between diastole and systole was measured. Using finite element procedures, we determined the equivalent pulse pressure loading that should be applied to the wall of a model where thrombus was digitally removed, to yield the same sac volumetric increase caused by applying the luminal pulse pressure to the model with thrombus. The equivalent instead of the measured pulse pressure was used in the distensibility expression. For a relative volumetric thrombus deposition (V ILT) of 50 %, a 62 % distensibility underestimation resulted when thrombus role was neglected. A strong linear correlation was observed between distensibility underestimation and V ILT. To assess the potential value of noninvasive wall distensibility measurement in rupture risk stratification, the role of thrombus on wall loading should be further investigated. |
Year | DOI | Venue |
|---|---|---|
2015 | 10.1007/s11517-014-1235-x | Med. Biol. Engineering and Computing |
Keywords | Field | DocType |
young s modulus | Hemodynamics,Biomedical engineering,Thrombus,Aortic aneurysm,Pulse pressure,Diastole,Abdominal aortic aneurysm,Systole,Aorta,Mathematics | Journal |
Volume | Issue | ISSN |
53 | 4 | 1741-0444 |
Citations | PageRank | References |
0 | 0.34 | 7 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Eleni Metaxa | 1 | 1 | 1.38 |
| Nikolaos Kontopodis | 2 | 0 | 1.01 |
| Vasileios Vavourakis | 3 | 6 | 3.15 |
| Konstantinos Tzirakis | 4 | 2 | 1.13 |
| Christos V Ioannou | 5 | 2 | 1.46 |
| Yannis Papaharilaou | 6 | 1 | 1.38 |