Name
Title | ||
|---|---|---|
Distinguishing between driver and passenger mutations in individual cancer genomes by network enrichment analysis. |
Abstract | ||
|---|---|---|
In somatic cancer genomes, delineating genuine driver mutations against a background of multiple passenger events is a challenging task. The difficulty of determining function from sequence data and the low frequency of mutations are increasingly hindering the search for novel, less common cancer drivers. The accumulation of extensive amounts of data on somatic point and copy number alterations necessitates the development of systematic methods for driver mutation analysis. |
Year | DOI | Venue |
|---|---|---|
2014 | 10.1186/1471-2105-15-308 | BMC Bioinformatics |
Keywords | Field | DocType |
biological sciences,mutation,microarrays,genomics,roc curve,bioinformatics,algorithms | Genome,Biology,Somatic cell,Genomics,Data sequences,Bioinformatics,Gene regulatory network,Genetics,DNA microarray,Cancer,Mutation | Journal |
Volume | Issue | ISSN |
15 | 1 | 1471-2105 |
Citations | PageRank | References |
8 | 0.49 | 11 |
Authors | ||
3 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Simon Kebede Merid | 1 | 8 | 0.49 |
| Daria Goranskaya | 2 | 8 | 0.49 |
| Andrey Alexeyenko | 3 | 10 | 1.55 |