Name
Abstract | ||
|---|---|---|
This paper presents a hand-held microsystem based on new fully integrated magnetoresistive biochips for biomolecular recognition (DNA hybridization, antibody antigen interaction, etc.). Magnetoresistive chip surfaces are chemically treated, enabling the immobilization of probe biomolecules such as DNA or antibodies. Fluid handling is also integrated in the biochip. The proposed microsystem not only integrates the biochip, which is an array of 16times16 magnetoresistive sensors, but it also provides all the electronic circuitry for addressing and reading out each transducer. The proposed architecture and circuits were specifically designed for achieving a compact, programmable and portable microsystem. The microsystem also integrates a hand-held analyzer connected through a wireless channel. A prototype of the system was already developed and detection of magnetic nanoparticles was obtained. This indicates that the system may be used for magnetic label based bioassays |
Year | DOI | Venue |
|---|---|---|
2006 | 10.1109/TCSI.2006.884420 | Circuits and Systems I: Regular Papers, IEEE Transactions |
Keywords | Field | DocType |
biomolecular electronics,biosensors,magnetoresistive devices,microsensors,biological analysis,biomolecular recognition,fluid handling,hand-held microsystem architecture,integrated magnetoresistive biochips,magnetic nanoparticles detection,magnetoresistive sensor,Biochip,biological analysis,magnetoresistive sensor,microsystem | Transducer,Microsystem,Nanotechnology,Biochip,Antibody antigen,Electronic engineering,Chip,Biosensor,Electronic circuit,Spectrum analyzer,Mathematics | Journal |
Volume | Issue | ISSN |
53 | 11 | 1549-8328 |
Citations | PageRank | References |
5 | 2.52 | 0 |
Authors | ||
10 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Moisés Simões Piedade | 1 | 43 | 14.31 |
| Leonel Augusto Sousa | 2 | 5 | 3.20 |
| T. M. Almeida | 3 | 14 | 7.04 |
| J. Germano | 4 | 24 | 9.84 |
| Bertinho Andrade da Costa | 5 | 5 | 2.52 |
| João Miranda Lemos | 6 | 54 | 10.64 |
| Paulo P. Freitas | 7 | 48 | 17.51 |
| H. A. Ferreira | 8 | 12 | 6.09 |
| Filipe Arroyo Cardoso | 9 | 14 | 7.04 |
| de Almeida, T.M. | 10 | 5 | 2.52 |