Title
Evol and ProDy for bridging protein sequence evolution and structural dynamics.
Abstract
Correlations between sequence evolution and structural dynamics are of utmost importance in understanding the molecular mechanisms of function and their evolution. We have integrated Evol, a new package for fast and efficient comparative analysis of evolutionary patterns and conformational dynamics, into ProDy, a computational toolbox designed for inferring protein dynamics from experimental and theoretical data. Using information-theoretic approaches, Evol coanalyzes conservation and coevolution profiles extracted from multiple sequence alignments of protein families with their inferred dynamics.
Year
DOI
Venue
2014
10.1093/bioinformatics/btu336
BIOINFORMATICS
Field
DocType
Volume
Sequence alignment,Protein family,Coevolution,Protein sequencing,Computer science,Bridging (networking),Protein dynamics,Bioinformatics,Evolutionary biology,Protein structure
Journal
30
Issue
ISSN
Citations 
18
1367-4803
8
PageRank 
References 
Authors
0.53
16
7
Name
Order
Citations
PageRank
Ahmet Bakan1614.99
Anindita Dutta280.53
Wenzhi Mao3181.86
Ying Liu480.53
Chakra Chennubhotla58912.70
Timothy R. Lezon6162.27
Ivet Bahar736139.41