Title
Inferring and Learning from Neuronal Correspondences.
Abstract
We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences combine data effectively from cross-animal studies to make joint inferences about behavioral decision making that are not possible with the data from a single animal. We focus on data collection, machine learning, and prediction in the representative and long-studied invertebrate nervous system of the European medicinal leech. Acknowledging the computational intractability of the general problem of identifying correspondences among neurons, we introduce efficient computational procedures for matching neurons across animals. The methods include techniques that adjust for missing cells or additional cells in the different data sets that may reflect biological or experimental variation. The methods highlight the value harnessing inference and learning in new kinds of computational microscopes for multiunit neurobiological studies.
Year
Venue
Field
2015
CoRR
Data collection,Data set,Computer science,Inference,Artificial intelligence,Behavioral decision making,Machine learning
DocType
Volume
Citations 
Journal
abs/1501.05973
0
PageRank 
References 
Authors
0.34
23
5
Name
Order
Citations
PageRank
Ashish Kapoor11833119.72
E. Paxon Frady231.10
Stefanie Jegelka379246.31
William B. Kristan Jr.400.68
Eric Horvitz594021058.25