Paper Info
Title
Dogsd: The Dog And Wolf Genome Snp Database
Abstract
The rapid advancement of next-generation sequencing technology has generated a deluge of genomic data from domesticated dogs and their wild ancestor, grey wolves, which have simultaneously broadened our understanding of domestication and diseases that are shared by humans and dogs. To address the scarcity of single nucleotide polymorphism (SNP) data provided by authorized databases and to make SNP data more easily/friendly usable and available, we propose DoGSD (http://dogsd.big.ac.cn), the first canidae-specific database which focuses on whole genome SNP data from domesticated dogs and grey wolves. The DoGSD is a web-based, open-access resource comprising similar to 19 million high-quality whole-genome SNPs. In addition to the dbSNP data set (build 139), DoGSD incorporates a comprehensive collection of SNPs from two newly sequenced samples (1 wolf and 1 dog) and collected SNPs from three latest dog/wolf genetic studies (7 wolves and 68 dogs), which were taken together for analysis with the population genetic statistics, Fst. In addition, DoGSD integrates some closely related information including SNP annotation, summary lists of SNPs located in genes, synonymous and non-synonymous SNPs, sampling location and breed information. All these features make DoGSD a useful resource for in-depth analysis in dog-/wolf-related studies.
Year
DOI
Venue
2015
10.1093/nar/gku1174
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Genome,Population,Domestication,Biology,Tag SNP,dbSNP,Single-nucleotide polymorphism,SNP annotation,Genetics,SNP
Journal
43
Issue
ISSN
Citations 
D1
0305-1048
3
PageRank 
References 
Authors
1.55
3
12
Name
Order
Citations
PageRank
Bing Bai131.55
Wenming Zhao26916.60
Bixia Tang34410.31
Yanqing Wang4152.73
Lu Wang531.89
Zhang Zhang617228.00
He-Chuan Yang731.89
Yan-Hu Liu831.89
Jun-Wei Zhu941.90
David M Irwin1032.56
Guodong Wang1116824.74
Ya-Ping Zhang12114.66