Title
Learning Structured Models for Segmentation of 2-D and 3-D Imagery
Abstract
Efficient and accurate segmentation of cellular structures in microscopic data is an essential task in medical imaging. Many state-of-the-art approaches to image segmentation use structured models whose parameters must be carefully chosen for optimal performance. A popular choice is to learn them using a large-margin framework and more specifically structured support vector machines (SSVM). Although SSVMs are appealing, they suffer from certain limitations. First, they are restricted in practice to linear kernels because the more powerful nonlinear kernels cause the learning to become prohibitively expensive. Second, they require iteratively finding the most violated constraints, which is often intractable for the loopy graphical models used in image segmentation. This requires approximation that can lead to reduced quality of learning. In this paper, we propose three novel techniques to overcome these limitations. We first introduce a method to “kernelize” the features so that a linear SSVM framework can leverage the power of nonlinear kernels without incurring much additional computational cost. Moreover, we employ a working set of constraints to increase the reliability of approximate subgradient methods and introduce a new way to select a suitable step size at each iteration. We demonstrate the strength of our approach on both 2-D and 3-D electron microscopic (EM) image data and show consistent performance improvement over state-of-the-art approaches.
Year
DOI
Venue
2015
10.1109/TMI.2014.2376274
IEEE Trans. Med. Imaging
Keywords
Field
DocType
image processing,mitochondria,kernel,learning artificial intelligence,kernel methods,neurophysiology,structured prediction,segmentation,image segmentation,support vector machines,electron microscopy,labeling,computer vision
Subgradient method,Computer science,Structured prediction,Image segmentation,Artificial intelligence,Kernel (linear algebra),Computer vision,Pattern recognition,Segmentation,Support vector machine,Graphical model,Kernel method,Machine learning
Journal
Volume
Issue
ISSN
34
5
0278-0062
Citations 
PageRank 
References 
6
0.47
44
Authors
7
Name
Order
Citations
PageRank
Aurelien Lucchi1241989.45
Pablo Márquez-Neila2527.03
Carlos Becker31648.91
Yunpeng Li457845.91
Kevin Smith5243088.78
Graham Knott61208.66
Pascal Fua712768731.45