Title
Attenuation correction synthesis for hybrid PET-MR scanners: application to brain studies.
Abstract
Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not directly provide a patient-specific attenuation map. The aim of the proposed work is to improve attenuation correction for PET/MR scanners by generating synthetic CTs and attenuation maps. The synthetic images are generated through a multi-atlas information propagation scheme, locally matching the MRI-derived patient's morphology to a database of MRI/CT pairs, using a local image similarity measure. Results show significant improvements in CT synthesis and PET reconstruction accuracy when compared to a segmentation method using an ultrashort-echo-time MRI sequence and to a simplified atlas-based method.
Year
DOI
Venue
2014
10.1109/TMI.2014.2340135
IEEE Trans. Med. Imaging
Keywords
Field
DocType
Attenuation correction, image synthesis, positron emission tomography/magnetic resonance (PET/MR)
Computer vision,Similarity measure,Segmentation,Computed tomography,Artificial intelligence,Positron emission tomography,Correction for attenuation,Information propagation,Attenuation,Mathematics,Magnetic resonance imaging
Journal
Volume
Issue
ISSN
33
12
0278-0062
Citations 
PageRank 
References 
43
2.20
13
Authors
15
Name
Order
Citations
PageRank
Ninon Burgos19411.64
Manuel Jorge Cardoso247839.26
Kris Thielemans3492.87
Marc Modat489872.33
Stefano Pedemonte5636.80
John Dickson6553.74
Anna Barnes7555.07
Rebekah Ahmed8432.20
Colin J Mahoney9432.20
Jonathan M Schott10613.39
J S Duncan1136838.49
David Atkinson12676.89
Simon R Arridge1353274.17
Brian F. Hutton149814.33
Sébastien Ourselin152499237.61