Title
Manual and automated intima-media thickness and diameter measurements of the common carotid artery in patients with renal failure disease
Abstract
The objective of this study was to investigate differences in intima-media thickness (IMT) and diameter (D) measurements of the common carotid artery (CCA) in ultrasound imaging in normal subjects and renal failure disease (RFD) patients. Manual measurements by two experts and automated segmentation measurements (based on snakes and active contour models (ACM)) were carried out on 73 normal subjects, and 80 RFD patients. Statistical analysis was carried out using the Wilcoxon rank-sum test at p<0.05. Results demonstrated that the mean IMT and D measurements were significantly higher for the RFD group versus the normal group. Moreover, there was no significant difference between the manual and automated measurements. The ACM segmentation was slightly more accurate than segmentation based on snakes. Further work is needed to validate these findings on a larger group of subjects. We use two different automated segmentation systems, based on snakes and on active contour models.We performed measurements of the carotid intima-media thickness (IMT) and diameter (D) in renal failure disease patients.Statistical significant differences for the IMT and the D, between the normal and the RFD patients were found.The ACM segmentation was slightly more accurate than segmentation based on snakes.
Year
DOI
Venue
2014
10.1016/j.compbiomed.2014.08.003
Computers in Biology and Medicine
Keywords
DocType
Volume
Carotid diameter,Common carotid artery,Intima-media thickness,Renal failure disease,Segmentation,Ultrasound imaging
Journal
53
Issue
ISSN
Citations 
C
0010-4825
4
PageRank 
References 
Authors
0.41
8
5
Name
Order
Citations
PageRank
C P Loizou122820.37
Takis Kasparis241653.68
Theodoros Lazarou340.75
Constantinos S. Pattichis438243.89
Marios Pantziaris523421.31