Title
Fast generation of T2* maps in the entire range of clinical interest: application to thalassemia major patients.
Abstract
T2⁎ maps obtained by the processing of multiecho MR sequences can be useful in several clinical applications. T2⁎ map generation procedures should join a processing time compatible with on-line image analysis with a good precision in the entire T2⁎ range of clinical interest. Fast generation of T2⁎ maps can be achieved by the estimation of the T2⁎ values by the weighted linear fitting of the logarithm of the signal (WLSL) method. This approach fails if the signal decay diverges from a pure exponential decay, as happens at low T2⁎ values where the rapid decay in the signal intensity leads to a plateau in the later echo times (TE). The proposed method implements the automatic truncation of the signal decay curves to be fitted in order to compensate for the signal collapse at low T2⁎ values, allowing the extension of the WLSL method through the entire clinical range of T2⁎ values.
Year
DOI
Venue
2015
10.1016/j.compbiomed.2014.10.020
Computers in Biology and Medicine
Keywords
DocType
Volume
T2⁎ mapping,Iron overload,Relaxometry,Magnetic resonance imaging,Thalassemia
Journal
56
Issue
ISSN
Citations 
C
0010-4825
0
PageRank 
References 
Authors
0.34
0
10