Title
A computational method of predicting regulatory interactions in Arabidopsis based on gene expression data and sequence information.
Abstract
•SVM is explored to predict regulatory interactions in Arabidopsis. Experimentally validated regulatory relationships were collected as the positive samples.•Negative training samples were randomly selected TF–target pairs under some strategies.•Each gene pair was represented by incorporating the expression data and sequence information.•Through the jackknife test, our method reached an overall accuracy of 98.39% with the sensitivity of 94.88%, and the specificity of 93.82%.
Year
DOI
Venue
2014
10.1016/j.compbiolchem.2014.04.003
Computational Biology and Chemistry
Keywords
Field
DocType
Transcription factor,Expression profile,Sequence information,Support vector machines
Arabidopsis,Jackknife resampling,Biology,Support vector machine,Gene expression,Bioinformatics,Genetics,Transcription factor
Journal
Volume
ISSN
Citations 
51
1476-9271
0
PageRank 
References 
Authors
0.34
10
5
Name
Order
Citations
PageRank
Xiaoqing Yu17511.53
Hongyun Gao2141.15
Xiaoqi Zheng3596.32
Chun Li4111.35
Jun Wang5244.32