Title
A priori assessment of data quality in molecular phylogenetics.
Abstract
Sets of sequence data used in phylogenetic analysis are often plagued by both random noise and systematic biases. Since the commonly used methods of phylogenetic reconstruction are designed to produce trees it is an important task to evaluate these trees a posteriori. Preferably, however, one would like to assess the suitability of the input data for phylogenetic analysis a priori and, if possible, obtain information on how to prune the data sets to improve the quality of phylogenetic reconstruction without introducing unwarranted biases. In the last few years several different approaches, algorithms, and software tools have been proposed for this purpose. Here we provide an overview of the state of the art and briefly discuss the most pressing open problems.
Year
DOI
Venue
2014
10.1186/s13015-014-0022-4
Algorithms for Molecular Biology
Keywords
Field
DocType
bioinformatics,algorithms
Data mining,Data set,Data quality,Phylogenetic tree,Molecular phylogenetics,Computer science,A priori and a posteriori,Random noise,Software,Phylogenomics,Bioinformatics
Journal
Volume
Issue
ISSN
9
1
1748-7188
Citations 
PageRank 
References 
0
0.34
14
Authors
6
Name
Order
Citations
PageRank
Bernhard Misof1111.44
Karen Meusemann271.43
Björn Marcus von Reumont360.70
Patrick Kück4101.04
Sonja J. Prohaska500.34
Peter F. Stadler61839152.96