Title
Automatic segmentation of basal ganglia iron deposits from structural MRI.
Abstract
Brain iron deposits have recently been suggested as biomarkers for small brain vessel diseases. Here, we present a novel, automated method for segmenting brain iron deposits in the basal ganglia from structural MRI data. It is based on minimum-variance clustering of intensities from T1and T2∗-weighted volumes, and a supervised cluster selection algorithm. This method was evaluated with MR data from 24 subjects and compared with iron deposit masks segmented manually by an experienced rater. A median Jaccard similarity index of 0.64 between manual and automatically generated segmentation masks is promising and encourages further investigations to improve the computing speed and accuracy of the method.
Year
Venue
Field
2011
MIUA
Pattern recognition,Segmentation,Computer science,Selection algorithm,Artificial intelligence,Jaccard index,Cluster analysis,Basal ganglia,Small brain
DocType
Citations 
PageRank 
Conference
0
0.34
References 
Authors
3
8