Title
SimConcept: A Hybrid Approach for Simplifying Composite Named Entities in Biomedicine.
Abstract
Many text-mining studies have focused on the issue of named entity recognition and normalization, especially in the field of biomedical natural language processing. However, entity recognition is a complicated and difficult task in biomedical text. One particular challenge is to identify and resolve composite named entities, where a single span refers to more than one concept(e.g., BRCA1/2). Most bioconcept recognition and normalization studies have either ignored this issue, used simple ad-hoc rules, or only handled coordination ellipsis, which is only one of the many types of composite mentions studied in this work. No systematic methods for simplifying composite mentions have been previously reported, making a robust approach greatly needed. To this end, we propose a hybrid approach by integrating a machine learning model with a pattern identification strategy to identify the antecedent and conjuncts regions of a concept mention, and then reassemble the composite mention using those identified regions. Our method, which we have named SimConcept, is the first method to systematically handle most types of composite mentions. Our method achieves high performance in identifying and resolving composite mentions for three fundamental biological entities: genes (89.29% in F-measure), diseases (85.52% in F-measure) and chemicals (84.04% in F-measure). Furthermore, our results show that, using our SimConcept method can subsequently help improve the performance of gene and disease concept recognition and normalization.
Year
DOI
Venue
2014
10.1145/2649387.2649420
BCB
Keywords
Field
DocType
language parsing and understanding,algorithms,speech recognition and synthesis,name entity normalization,name entity recognition,mention simplification,conditional random field,natural language processing,text analysis
Conditional random field,Normalization (statistics),Computer science,Concept recognition,Biomedicine,Artificial intelligence,Bioinformatics,Named-entity recognition,Machine learning,Pattern identification
Conference
Volume
Citations 
PageRank 
2014
6
0.46
References 
Authors
47
3
Name
Order
Citations
PageRank
Chih-Hsuan Wei154627.43
Robert Leaman291439.98
Zhiyong Lu32735171.27