Paper Info
Title
Comparison of CFD-Based and Bernoulli-Based Pressure Drop Estimates across the Aortic Valve Enabled by Shape-Constrained Deformable Segmentation of Cardiac CT Images.
Abstract
The aortic valve area (AVA) and the pressure drop (PD) across the aortic valve are important quantities for characterizing an aortic valve stenosis. Using the Bernoulli equation and mass conservation, a relation between both quantities can be derived. We developed a simulation pipeline to assess the accuracy of this relation for realistic patient anatomies and blood flow rates. The key element of the pipeline is a shape-constrained deformable model (SCDM) for the segmentation of the aortic valve, the ascending aorta and the left ventricle over the cardiac cycle in cardiac CT images. Efficient segmentation enabled application of the simulation pipeline to cardiac CT image sequences of 22 patients. Planimetric AVA and Bernoulli-based PD estimates were computed from the same segmentation results. The resulting PD estimates show a high correlation (R = 0.97), but Bernoulli-based PD results are on average 25% smaller than the CFD-based results. The results contribute to a better understanding and interpretation of clinically used quantities such as the AVA and the PD.
Year
DOI
Venue
2014
10.1007/978-3-319-12057-7_24
BIOMEDICAL SIMULATION
Field
DocType
Volume
Biomedical engineering,Aortic valve stenosis,Blood flow,Segmentation,Computer science,Internal medicine,Cardiology,Aortic valve,Ventricle,Cardiac cycle,Ascending aorta,Bernoulli's principle
Conference
8789
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
6
6
Name
Order
Citations
PageRank
Jochen Peters128425.51
Angela Lungu200.34
F M Weber38812.08
Irina Wächter-Stehle4112.69
D R Hose5314.48
Jürgen Weese677492.69