Title | ||
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Applying a decision support system in clinical practice: results from melanoma diagnosis. |
Abstract | ||
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The work reported in this paper investigates the use of a decision-support tool for the diagnosis of pigmented skin lesions in a real-world clinical trial with 511 patients and 3827 lesion evaluations. We analyzed a number of outcomes of the trial, such as direct comparison of system performance in laboratory and clinical setting, the performance of physicians using the system compared to a control dermatologist without the system, and repeatability of system recommendations. The results show that system performance was significantly less in the real-world setting compared to the laboratory setting (c-index of 0.87 vs. 0.94, p = 0.01). Dermatologists using the system achieved a combined sensitivity of 85% and combined specificity of 95%. We also show that the process of acquiring lesion images using digital dermoscopy devices needs to be standardized before sufficiently high repeatability of measurements can be assured. |
Year | Venue | Field |
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2007 | AMIA | Lesion,Pigmented skin,Decision support system,Clinical Practice,Clinical trial,Radiology,Melanoma,Surgery,Medicine,Repeatability |
DocType | ISSN | Citations |
Conference | 1942-597X | 1 |
PageRank | References | Authors |
0.35 | 4 | 4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Stephan Dreiseitl | 1 | 338 | 34.80 |
Michael Binder | 2 | 5 | 1.21 |
Staal Vinterbo | 3 | 361 | 32.66 |
Harald Kittler | 4 | 148 | 11.46 |