Title
Applying a decision support system in clinical practice: results from melanoma diagnosis.
Abstract
The work reported in this paper investigates the use of a decision-support tool for the diagnosis of pigmented skin lesions in a real-world clinical trial with 511 patients and 3827 lesion evaluations. We analyzed a number of outcomes of the trial, such as direct comparison of system performance in laboratory and clinical setting, the performance of physicians using the system compared to a control dermatologist without the system, and repeatability of system recommendations. The results show that system performance was significantly less in the real-world setting compared to the laboratory setting (c-index of 0.87 vs. 0.94, p = 0.01). Dermatologists using the system achieved a combined sensitivity of 85% and combined specificity of 95%. We also show that the process of acquiring lesion images using digital dermoscopy devices needs to be standardized before sufficiently high repeatability of measurements can be assured.
Year
Venue
Field
2007
AMIA
Lesion,Pigmented skin,Decision support system,Clinical Practice,Clinical trial,Radiology,Melanoma,Surgery,Medicine,Repeatability
DocType
ISSN
Citations 
Conference
1942-597X
1
PageRank 
References 
Authors
0.35
4
4
Name
Order
Citations
PageRank
Stephan Dreiseitl133834.80
Michael Binder251.21
Staal Vinterbo336132.66
Harald Kittler414811.46