Title
Joint parametric reconstruction and motion correction framework for dynamic PET data.
Abstract
In this paper we propose a novel algorithm for jointly performing data based motion correction and direct parametric reconstruction of dynamic PET data. We derive a closed form update for the penalised likelihood maximisation which greatly enhances the algorithm's computational efficiency for practical use. Our algorithm achieves sub-voxel motion correction residual with noisy data in the simulation-based validation and reduces the bias of the direct estimation of the kinetic parameter of interest. A preliminary evaluation on clinical brain data using [18 F] Choline shows improved contrast for regions of high activity. The proposed method is based on a data-driven kinetic modelling method and is directly applicable to reversible and irreversible PET tracers, covering a range of clinical applications.
Year
DOI
Venue
2014
10.1007/978-3-319-10404-1_15
Lecture Notes in Computer Science
Keywords
Field
DocType
Dynamic PET,direct parametric reconstruction,motion correction,optimisation transfer,kinetic analysis
Iterative reconstruction,Residual,Computer vision,Noisy data,Kinetic analysis,Pattern recognition,Computer science,Parametric statistics,Artificial intelligence,Motion correction
Conference
Volume
Issue
ISSN
8673
Pt 1
0302-9743
Citations 
PageRank 
References 
1
0.36
9
Authors
9
Name
Order
Citations
PageRank
Jieqing Jiao1123.24
Alexandre Bousse282.96
Kris Thielemans333.43
P. J. Markiewicz4184.20
Ninon Burgos59411.64
David Atkinson6676.89
Simon R Arridge753274.17
Brian F. Hutton89814.33
Sébastien Ourselin92499237.61