Paper Info
Title
Multi-Modal Validation Framework Of Mitral Valve Geometry And Functional Computational Models
Abstract
Computational models of the mitral valve (MV) exhibit significant potential for patient-specific surgical planning. Recently, these models have been advanced by incorporating MV tissue structure, non-linear material properties, and more realistic chordae tendineae architecture. Despite advances, only limited ground-truth data exists to validate their ability to accurately simulate MV closure and function. The validation of the underlying models will enhance modeling accuracy and confidence in the simulated results. A necessity towards this aim is to develop an integrated pipeline based on a comprehensive in-vitro flow loop setup including echocardiography techniques (Echo) and micro-computed tomography. Building on [1] we improved the acquisition protocol of the proposed experimental setup for in-vitro Echo imaging, which enables the extraction of more reproducible and accurate geometrical models, using state-of-the art image processing and geometric modeling techniques. Based on the geometrical parameters from the Echo MV models captured during diastole, a bio-mechanical model is derived to estimate MV closure geometry. We illustrate the framework on two data sets and show the improvements obtained from the novel Echo acquisition protocol and improved bio-mechanical model.
Year
DOI
Venue
2014
10.1007/978-3-319-14678-2_25
Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges
DocType
Volume
ISSN
Conference
8896
0302-9743
Citations 
PageRank 
References 
2
0.40
4
Authors
12
Name
Order
Citations
PageRank
Sasa Grbic18213.77
Thomas F. Easley230.76
Tommaso Mansi345445.94
Charles H. Bloodworth431.10
Eric L. Pierce531.10
Ingmar Voigt616018.48
Dominik Neumann7839.40
Julian Krebs8313.57
Yuh David D915414.38
Morten O. Jensen1031.10
Dorin Comaniciu118389601.83
Ajit P. Yoganathan12505.98