Title
Event detection by feature unpredictability in phase-contrast videos of cell cultures.
Abstract
In this work we propose a novel framework for generic event monitoring in live cell culture videos, built on the assumption that unpredictable observations should correspond to biological events. We use a small set of event-free data to train a multioutput multikernel Gaussian process model that operates as an event predictor by performing autoregression on a bank of heterogeneous features extracted from consecutive frames of a video sequence. We show that the prediction error of this model can be used as a probability measure of the presence of relevant events, that can enable users to perform further analysis or monitoring of large-scale non-annotated data. We validate our approach in two phase-contrast sequence data sets containing mitosis and apoptosis events: a new private dataset of human bone cancer (osteosarcoma) cells and a benchmark dataset of stem cells.
Year
DOI
Venue
2014
10.1007/978-3-319-10470-6_20
Lecture Notes in Computer Science
Keywords
Field
DocType
Event detection,mitosis,apoptosis,cell cultures,phase-contrast imaging
Event monitoring,Phase contrast microscopy,Autoregressive model,Computer vision,Mean squared prediction error,Pattern recognition,Computer science,Probability measure,Multikernel,Gaussian process,Artificial intelligence,Small set
Conference
Volume
Issue
ISSN
8674
Pt 2
0302-9743
Citations 
PageRank 
References 
2
0.40
9
Authors
7
Name
Order
Citations
PageRank
Melih Kandemir118216.91
Jose C Rubio280.83
Ute Schmidt320.40
Christian Wojek440.77
Johannes Welbl51477.25
Björn Ommer620.40
Fred A. Hamprecht796276.24