Title
Personalized modeling of prostate deformation based on elastography for MRI-TRUS registration
Abstract
Fusion of pre- and intra-operative imaging modalities allows the accurate targeting of prostate interventions. We propose a personalized statistical motion model (PSMM) for the deformable registration of prostate magnetic resonance (MR) and 3D transrectal ultrasound (TRUS) images. Comparing to traditional statistical motion model (SMM) methods, for the first time, the biomechanical information obtained from elastography is incorporated into a finite element (FE) model, which is created from preoperative MR images. PSMM is then constructed from training data generated by simulating the prostate deformation from the personalized FE model with realistic boundary conditions. Finally, prostate MR and TRUS images are registered by integrating the PSMM into a robust point matching (RPM) framework. Using data acquired from phantoms, the efficiency of the PSMM and the accuracy of MRI-TRUS registration were evaluated. The mean target registration error was less than 1.7mm, which demonstrates our PSMM can achieve more physically plausible deformation estimation and accurate registration.
Year
DOI
Venue
2014
10.1109/ISBI.2014.6867987
ISBI
Keywords
DocType
ISSN
CANCER,BIOPSY
Conference
1945-7928
Citations 
PageRank 
References 
0
0.34
4
Authors
7
Name
Order
Citations
PageRank
Yi Wang1499.35
Dong Ni236737.37
Jing Qin3110995.43
Xin Yang4799.59
Xiaoyan Xie500.34
Muqing Lin600.34
Pheng-Ann Heng73565280.98