Paper Info
Title
Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction.
Abstract
Pulse Transit Time (PTT) is the time it takes for an arterial pulsation to travel from the heart to a peripheral site. In recent times, PTT has been advocated as a marker for assessing increased vascular resistance. However, the reliability of PTT as a marker for cardiovascular risks and its inverse relation to beat-to-beat blood pressure is still being investigated. In order to validate the technique as a reliable marker of vascular resistance, PTT measurements were made using photoplethysmographic (PPG) signals obtained from multiple measurement sites in 12 healthy volunteers undergoing right hand immersion in ice water for 30 secs. PTT measurements were made from the ear canal (EC), the left (LIF) and right index fingers (RIF) using custom made photoplethysmographic probes. Activation of the sympathetic nervous system during the ice water immersion caused an increase in vascular resistance, which is associated with an increase in mean arterial pressure and a decrease in PTT in all measurement sites. However, the change in PTT was much larger in the RIF when compared to the LIF and the EC. This demonstrates the cerebral flow autoregulation and the profound peripheral vasoconstriction seen in the right hand. After the ice immersion period, the mean PTT measured from the EC returned to baseline, whereas the LIF PTT exceeded baseline values. This is due to the local vasodilation resulted from the activation of a thermoregulation mechanism.
Year
DOI
Venue
2014
10.1109/EMBC.2014.6943998
EMBC
Keywords
Field
DocType
multiple measurement sites,ec,right hand immersion,photoplethysmography,time 30 s,blood pressure measurement,sympathetic nervous system activation,neurophysiology,left index fingers,cerebral flow autoregulation,local vasodilation,arterial pulsation,beat-to-beat blood pressure,blood vessels,thermoregulation mechanism activation,peripheral site,right index fingers,mean ptt,inverse problems,rif,baseline values,cardiovascular system,lif ptt,ice immersion period,ptt measurement,photoplethysmographic signals,mean arterial pressure,multisite reflectance photoplethysmography,vascular resistance marker,artificially induced peripheral vasoconstriction,ppg,ear canal,pulse transit times,photoplethysmographic probes,inverse relation,heart,pulsatile flow,ptt reliability,ice water immersion,cardiovascular risks
Sympathetic nervous system,Peripheral,Computer science,Anesthesia,Pulse (signal processing),Blood pressure,Artificial intelligence,Vascular resistance,Vasodilation,Computer vision,Internal medicine,Photoplethysmogram,Cardiology,Mean arterial pressure
Conference
Volume
ISSN
Citations 
2014
1557-170X
1
PageRank 
References 
Authors
0.38
1
2
Name
Order
Citations
PageRank
K Budidha121.75
P A Kyriacou22016.60