Paper Info
Title
Automatic quantification of CT images for traumatic brain injury
Abstract
Traumatic brain injury (TBI) is a major health problem and the most common cause of permanent disability in people under the age of 40 years. In this paper, we present a fully automatic framework for the analysis of acute computed tomography (CT) images in TBI. Different pathologies common in TBI are quantified and all the information is combined for clinical outcome prediction in individual patients. We propose a multi-template approach for the registration of CT data, which improves the robustness and accuracy of spatial normalization. This is especially important for noisy CT data and TBI images with large areas of pathology. The tissue segmentation methods we use have been optimized to deal with these challenges. The methods we describe have been evaluated on acute CTs from 104 TBI patients. We demonstrate on this dataset that the prediction of dichotomized favorable or unfavorable outcome can be made with an accuracy of 79%.
Year
DOI
Venue
2014
10.1109/ISBI.2014.6867825
Biomedical Imaging
Keywords
DocType
ISSN
biological tissues,brain,computerised tomography,image registration,image segmentation,injuries,medical image processing,TBI,acute computed tomography images,automatic CT image quantification,dichotomized favorable outcome,image registration,multitemplate approach,permanent disability,spatial normalization,tissue segmentation,traumatic brain injury,CT,classification,multi-template1,prognosis,registration,segmentation,traumatic brain injury
Conference
1945-7928
Citations 
PageRank 
References 
0
0.34
0
Authors
4
Name
Order
Citations
PageRank
Juha Koikkalainen1604.78
Jyrki Lötjönen238833.95
Christian Ledig348927.08
Daniel Rueckert49338637.58