Title | ||
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A simple ion concentration measurement system using a microfluidic device with ISFET sensors |
Abstract | ||
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We present a newly developed measurement system using a microfluidic device designed to measure hydrogen ion concentrations (pH) in a relatively simple procedure that consumes only small amounts of sample solution. The device takes the form of a channel consisting of two inlets and one outlet connected together with a Y-shaped junction. Two ion-sensitive field-effect transistors (ISFETs) and an Ag/AgCl pseudo reference electrode are fitted into the device as a differential measurement circuit. The small size and high sensitivity of the ISFET sensors enable the measurement of small volumes of sample solution within a short time. The design principle and operation of the measurement system are very simple: a baseline solution (BLS) and sample solution are supplied into the device by a gravity-driven pump and the inflows of solutions are switched by adjusting the respective heights of the solution reservoirs. The measurement accuracy of a trial device was evaluated using standard solutions and diluted solutions after calibration. The maximum measurement errors for the standard solutions and 100-fold diluted solutions were 0.04 pH and 0.16 pH, respectively. |
Year | DOI | Venue |
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2014 | 10.1109/MHS.2014.7006164 | Micro-NanoMechatronics and Human Science |
Keywords | Field | DocType |
calibration,chemical variables measurement,hydrogen,ion sensitive field effect transistors,measurement errors,microchannel flow,microsensors,silver,silver compounds,Ag-AgCl,H2,ISFET sensors,Y-shaped junction,baseline solution,calibration,differential measurement circuit,gravity-driven pump,hydrogen ion concentration measurement accuracy,ion sensitive field effect transistors,measurement errors,microfluidic device,pseudo reference electrode,sample solution,solution reservoirs | ISFET,Reference electrode,Analytical chemistry,System of measurement,Microfluidics,Accuracy and precision,Transistor,Materials science,Standard solution,Calibration | Conference |
ISSN | Citations | PageRank |
2474-378X | 0 | 0.34 |
References | Authors | |
0 | 2 |
Name | Order | Citations | PageRank |
---|---|---|---|
Tsuyoshi Miura | 1 | 0 | 0.68 |
Akira Yamada | 2 | 0 | 2.03 |