Paper Info
Title
Live demonstration: Characterization of a wireless implantable infusion micropump for small animal research under simulated in vivo conditions
Abstract
Rodents are the most widely used animal model in the study of human disease and drug administration technologies suitable for use in rodents are therefore critically important in the development of new treatments. Implantable drug delivery devices provide site specific and controlled drug administration while eliminating frequent handling, tethers, and stress induction associated with other drug delivery methods. Although implantable pumps are commercially available, none are suitable for controlled chronic dosing experiments in mice. These commercial pumps possess one or more of the following deficiencies: too large, limited drug payload, limited lifetime due to single-use battery, single fixed flow rate, or inability to adjust flow rate after implantation.
Year
DOI
Venue
2014
10.1109/BioCAS.2014.6981685
BioCAS
Keywords
Field
DocType
biomems,diseases,drug delivery systems,microfluidics,micropumps,prosthetics,animal model,commercial pump drug payload,commercial pump lifetime,commercial pump size,controlled chronic dosing experiment,drug administration control,drug administration technology,flow rate adjustment,frequent handling elimination,human disease,implantable drug delivery device,in vivo condition simulation,live demonstration,patient treatment,rodent,single fixed flow rate,single-use battery,site specific drug administration,small animal research,stress induction,tether,wireless implantable infusion micropump characterization,wireless communication
Biomedical engineering,Computer science,Implantable Pump,In vivo,Micropump,Dosing,Drug delivery,Drug,Animal model,Drug administration
Conference
ISSN
Citations 
PageRank 
2163-4025
0
0.34
References 
Authors
1
4
Name
Order
Citations
PageRank
Cobo, A.M.100.34
Tu, H.M.200.34
Sheybani, R.300.34
Ellis Meng4267.10