Paper Info
Title
A multichannel current stimulator chip for spatiotemporal pattern stimulation of neural tissues.
Abstract
We developed a prototype very-large-scale integration chip of a multichannel current stimulator for stimulating neural tissues by utilizing 0.25 μm high-voltage complementary metal-oxide-semiconductor technology. Our designed chip has 20 output channels that are driven by five current buffers arranged in parallel; each buffer controls four output channels in time-sharing mode. The amplitude of a stimulation pulse can be controlled within a range of approximately ±100 μA/phase in each output channel. The stimulus parameters, e.g., amplitude and duration, are controlled separately for each channel by digital codes stored in built-in registers. Combinations of anode and cathode electrodes to pass the current can be changed online. We integrated our stimulator chip with a multielectrode array and studied the neuronal responses to multichannel current stimulations with various temporal patterns in mouse brain slices.
Year
DOI
Venue
2014
10.1109/EMBC.2014.6944750
EMBC
Keywords
Field
DocType
digital codes,bioelectric potentials,complementary metal-oxide-semiconductor technology,vlsi,neurophysiology,mouse brain slices,biomedical electrodes,anode electrodes,cmos integrated circuits,cathode electrodes,very large scale integration chip,multielectrode array,neural tissues,brain,neuronal responses,multichannel current stimulator chip,biological tissues,time-sharing mode,biomedical electronics,spatiotemporal pattern stimulation,patient treatment
Computer science,Chip,Electronic engineering,Neural tissues,Stimulation,Spatiotemporal pattern
Conference
Volume
ISSN
Citations 
2014
1557-170X
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Seiji Kameda1257.10
Yuki Hayashida2167.10
Yuta Tanaka301.35
Dai Akita400.34
Tetsuya Yagi514027.73