Paper Info
Title
Analysis of spontaneous MEG activity in mild cognitive impairment and Alzheimer's disease using Jensen's divergence.
Abstract
The aim of this study was to analyze the changes that mild cognitive impairment (MCI) and Alzheimer's disease (AD) elicit in brain dynamics. For this task, the spontaneous magnetoencephalographic (MEG) activity from 36 AD patients, 18 MCI subjects and 24 healthy controls was analyzed. A disequilibrium measure, Jensen's divergence, was used to estimate the irregularity of neural dynamics. Results revealed that AD patients displayed significant changes (p<;0.05) in the patterns of irregularity in comparison with MCI subjects and healthy controls. Slight differences between MCI subjects and elderly controls were also found. Our results suggest that AD progression is accompanied by region-specific patterns of abnormalities in the neural activity.
Year
DOI
Venue
2014
10.1109/EMBC.2014.6943886
EMBC
Keywords
Field
DocType
cognition,bioelectric potentials,diseases,brain dynamics,neurophysiology,geriatrics,neural activity,spontaneous meg activity analysis,region-specific patterns,alzheimer disease,elderly controls,spontaneous magnetoencephalographic activity analysis,magnetoencephalography,jensen divergence,mild cognitive impairment
Neuroscience,Disease,Neural activity,Psychology,Dementia,Cognitive impairment
Conference
Volume
ISSN
Citations 
2014
1557-170X
0
PageRank 
References 
Authors
0.34
2
6
Name
Order
Citations
PageRank
Jesús Poza15512.29
Carlos Gómez28615.72
María García322.43
Alejandro Bachiller462.95
Alberto Fernández55311.82
Roberto Hornero660367.74