Title
An intelligent system for vertebrate promoter recognition
Abstract
The Dragon Promoter Finder is an advanced system for promoter recognition in vertebrates. It uses a collection of models based on multisensor integration, signal processing, and artificial neural networks. The system uses newly developed sensors based on the statistical concept of oligonucleotide positional distributions in specific functional regions of DNA. These distributions are modeled as a set of position weight matrices of the most significant oligonucleotides. The authors calibrated the system to minimize the number of false-positive predictions for various prespecified sensitivity levels. When evaluated on a large and diverse human sequence set, it exhibited several times higher accuracy than several other publicly available general promoter recognition systems.
Year
DOI
Venue
2002
10.1109/MIS.2002.1024754
Intelligent Systems, IEEE
Keywords
Field
DocType
DNA,artificial intelligence,biology computing,genetics,neural nets,pattern recognition,sensitivity,sensor fusion,signal processing,zoology,DNA region,Dragon Promoter Finder,accuracy,artificial neural networks,biological gene activation,false-positive prediction minimization,gene transcription start site,intelligent system,multi-sensor integration,sensitivity levels,signal processing,vertebrate promoter recognition
Data mining,Biological activation,Gene,Transcription (biology),Computer science,Gene prediction,DNA,Vertebrate,Artificial intelligence,Computational biology,Artificial neural network
Journal
Volume
Issue
ISSN
17
4
1541-1672
Citations 
PageRank 
References 
18
3.51
5
Authors
4
Name
Order
Citations
PageRank
Vladimir B. Bajic1183.85
Allen Chong2657.96
S H Seah37910.51
Vladimir Brusic455163.37