Title
Cancer disease: integrative modelling approaches
Abstract
Cancer is a complex disease in which a variety of phenomena interact over a wide range of spatial and temporal scales. In this article a theoretical framework will be introduced that is capable of linking together such processes to produce a de- tailed model of vascular tumour growth. The model is for- mulated as a hybrid cellular automaton and contains submod- els that describe subcellular, cellular and tissue level features. Model simulations will be presented to illustrate the effect that coupling between these different elements has on the tu- mour's evolution and its response to chemotherapy.
Year
DOI
Venue
2006
10.1109/ISBI.2006.1625040
Arlington, VA
Keywords
Field
DocType
cancer,cellular automata,cellular biophysics,patient treatment,physiological models,tumours,cancer disease,cellular features,chemotherapy,hybrid cellular automaton,integrative modelling,subcellular features,tissue features,tumour evolution,vascular tumour growth
Cellular automaton,Cellular biophysics,Disease,Pattern recognition,Computer science,Automaton,Medical treatment,Artificial intelligence,Bioinformatics,Computational biology,Cancer,Patient treatment
Conference
ISSN
ISBN
Citations 
1945-7928
0-7803-9576-X
0
PageRank 
References 
Authors
0.34
1
4
Name
Order
Citations
PageRank
Helen Byrne101.01
Markus Owen2143.90
Tomas Alarcón3195.69
Philip K. Maini423836.37