Name
Title | ||
|---|---|---|
Three-dimensional surface reconstruction and fluorescent visualization of cardiac activation. |
Abstract | ||
|---|---|---|
Optical imaging of transmembrane potentials in cardiac tissue is a rapidly growing technique in cardiac electrophysiology. Traditional studies typically use a monocular imaging setup, thus limiting investigation to a restricted region of tissue. However, studies of large-scale wavefront dynamics, especially those during fibrillation and defibrillation, would benefit from visualization of the entire epicardial surface. To solve this problem, a panoramic cardiac visualization algorithm was developed which performs the two tasks of reconstruction of the surface geometry of the heart, and representation of the panoramic fluorescence information as a texture mapping onto the geometry that was previously created. This system permits measurement of epicardial electrodynamics over a geometrically realistic representation of the actual heart being studied. To verify the accuracy of the algorithm, the procedure was applied to synthetic images of a patterned ball; further verification was provided by application of the algorithm to a model heart placed in the experimental setup. Both sets of images produced mean registration image errors on the order of 2 pixels, corresponding to roughly 3 mm on the geometry. We demonstrate the algorithm by visualizing epicardial wavefronts on an isolated, perfused rabbit heart. |
Year | DOI | Venue |
|---|---|---|
2000 | 10.1109/10.871412 | IEEE transactions on bio-medical engineering |
Keywords | Field | DocType |
cardiology,texture mapping,bioelectric potentials,epicardial electrodynamics,isolated perfused rabbit heart,cardiac electrophysiology,panoramic cardiac visualization algorithm,cardiac activation,optical imaging,optical images,cardiac tissue,biological techniques,patterned ball,transmembrane potentials,image reconstruction,fluorescent visualization,synthetic images,algorithm accuracy verification,biological research technique,image registration,biomembranes,large-scale wavefront dynamics,geometrically realistic representation,three-dimensional surface reconstruction | Iterative reconstruction,Texture mapping,Computer vision,Surface reconstruction,Wavefront,Visualization,Computer science,Cardiac electrophysiology,Artificial intelligence,Pixel,Image registration | Journal |
Volume | Issue | ISSN |
47 | 10 | 0018-9294 |
Citations | PageRank | References |
4 | 1.21 | 8 |
Authors | ||
3 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Mark-Anthony Bray | 1 | 75 | 7.42 |
| Shien-fong Lin | 2 | 4 | 2.90 |
| J. p. Wikswo | 3 | 4 | 1.21 |