Title
Non-Extensive Entropy for CAD Systems of Breast Cancer Images
Abstract
Recent statistics show that breast cancer is a major cause of death among women in all of the world. Hence, early diagnostic with Computer Aided Diagnosis (CAD) systems is a very important tool. This task is not easy due to poor ultrasound resolution and large amount of patient data size. Then, initial image segmentation is one of the most important and challenging task. Among several meth- ods for medical image segmentation, the use of entropy for maximization the information between the foreground and background is a well known and applied technique. But, the traditional Shannon entropy fails to describe some physical systems with characteristics such as long-range and long- time interactions. Then, a new kind of entropy, called non- extensive entropy, has been proposed in the literature for generalizing the Shannon entropy. In this paper, we pro- pose the use of non-extensive entropy, also called q-entropy, applied in a CAD system for breast cancer classification in ultrasound of mammographic exams. Our proposal com- bines the non-extensive entropy, a level set formulation and a Support Vector Machine framework to achieve better per- formance than the current literature offers. In order to val- idate our proposal, we have tested our automatic protocol in a data base of 250 breast ultrasound images (100 benign and 150 malignant). With a cross-validation protocol, we demonstrate system's accuracy, sensitivity, specificity, posi- tive predictive value and negative predictive value as: 95%, 97%, 94%, 92% and 98%, respectively, in terms of ROC (Receiver Operating Characteristic) curves and Az areas.
Year
DOI
Venue
2006
10.1109/SIBGRAPI.2006.31
SIBGRAPI
Keywords
Field
DocType
biomedical ultrasonics,cancer,entropy,image segmentation,mammography,medical image processing,signal classification,support vector machines,CAD systems,Shannon entropy,automatic protocol,breast cancer classification,breast cancer images,breast ultrasound images,computer aided diagnosis systems,cross-validation protocol,level set formulation,mammographic exams,maximization,medical image segmentation,nonextensive entropy,q-entropy,receiver operating characteristic curves,support vector machine,ultrasound resolution
Breast ultrasound,Breast cancer classification,Mammography,Receiver operating characteristic,Pattern recognition,Computer science,Computer-aided diagnosis,Nonextensive entropy,Image segmentation,Artificial intelligence,Entropy (information theory)
Conference
ISSN
ISBN
Citations 
1530-1834
0-7695-2686-1
15
PageRank 
References 
Authors
0.87
4
4
Name
Order
Citations
PageRank
Paulo S. Rodrigues1467.12
Gilson A. Giraldi29821.93
Ruey-Feng Chang339534.88
Jasjit S. Suri41754128.89