Title
Contact-Based Stiffness Sensing of Human Eye
Abstract
Goldmann applanation tonometry is commonly used for measuring intraocular pressure (IOP) to diagnose glaucoma. However, the measured IOP by conventional applanation tonometry is valid only under the assumption that all subjects have the same structural eye stiffness. This paper challenges in vivo measurement of eye stiffness with a noninvasive approach and investigates individual differences of eye stiffness. Eye stiffness is defined by the applied force and displacement of the cornea. The displacement is detected based on captured images by a high resolution camera. The experimental results show that the measured stiffness nicely matches the analytical result that is derived from a simple spherical deformation model with an internal pressure. However, some subjects have different eye stiffness even with the same IOP. IOP with abnormal stiffness may be over/underestimated by conventional applanation tonometry. The proposed eye stiffness measurement can help detect the misestimated eye and it contributes to the early detection of glaucoma.
Year
DOI
Venue
2008
10.1109/TBME.2007.912650
Biomedical Engineering, IEEE Transactions
Keywords
Field
DocType
biomechanics,biomedical measurement,biomedical optical imaging,deformation,diseases,displacement measurement,elasticity,eye,Goldmann applanation tonometry,applied cornea force,contact-based stiffness sensing,cornea displacement,glaucoma diagnosis,high resolution camera,human eye,image capture,in vivo eye stiffness measurement,intraocular pressure measurement,spherical deformation model,structural eye stiffness,Contact method,glaucoma,human eye,stiffness sensing
Biomedical engineering,Early detection,Glaucoma,Computer science,Intraocular pressure,Artificial intelligence,Optometry,Biomechanics,Human eye,Computer vision,Goldmann applanation tonometry,Stiffness,Cornea
Journal
Volume
Issue
ISSN
55
2
0018-9294
Citations 
PageRank 
References 
5
1.20
1
Authors
4
Name
Order
Citations
PageRank
Kurita, Y.181.75
Kempf, R.281.75
Iida, Y.3112.98
Okude, J.451.20