Paper Info
Title
Association between short term and long term communication in pathological autonomic control.
Abstract
Autonomic Information Flow (AIF) reflects the time scale dependence of autonomic communications such as vagal, sympathetic, and slower rhythms and their complex interplay. We investigated the hypothesis that pathologically disturbed short term control is associated with simplified complex long term control. This particular characteristic of altered autonomic communication was evaluated in different medical patient groups. Holter recordings were assessed in patients with multiple organ dysfunction (MODS) (26 survivors, 10 non-survivors); with heart failure (14 low risk-without history of aborted cardiac arrest (CA), 13 high risk--with history of CA); with idiopathic dilated cardiomyopathy (IDC) (26 low risk, 11 high risk of CA), after myocardial infarction (MI) (1221 low risk--survivors, 55 high risk--non-survivors); after abdominal aorta surgery (AAS, 32 length of stay in hospital LOS>7 days, 62 LOS < or =7 days). AIF of short and long time scales was investigated. We found a fundamental association of increased short term randomness and decreased long term randomness due to pathology. Concerning risk, high risk patients were characterized by increased short term complexity and decreased long term complexity in all patients groups with the exception of the IDC patients. We conclude that different time scales of AIF represent specific pathophysiological aspects of altered autonomic communication and control. The association of altered short term control with simplified long term behavior might be a pathophysiologically relevant compensation mechanism in the case of a disturbed fastest actuator. This knowledge might be useful for the development of comprehensive therapeutic strategies besides the predictive implications.
Year
DOI
Venue
2006
10.1109/IEMBS.2006.260858
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
Keywords
DocType
Volume
disturbed fastest actuator,multiple organ dysfunction,autonomic information flow,biocontrol,diseases,aborted cardiac arrest,idiopathic dilated cardiomyopathy,neurophysiology,myocardial infarction,long term communication,autonomic communication,pathological autonomic control,cardiovascular system,short term communication,abdominal aorta surgery,comprehensive therapeutic strategies,heart failure,information flow,myocardial infarct
Conference
1
ISSN
ISBN
Citations 
1557-170X
1-4244-003303
0
PageRank 
References 
Authors
0.34
2
12
Name
Order
Citations
PageRank
Dirk Hoyer13912.37
B Frank200.34
Ch Götze300.34
R Baranowski400.34
J J Zebrowski500.34
M Vallverdú600.34
M Palacios700.34
P Caminal800.34
A Bayés de Luna900.34
P K Stein1000.34
G Schmidt1100.34
H Schmidt1200.34