Name
Title | ||
|---|---|---|
Noninvasive measurement of total hemoglobin and hemoglobin derivatives using multiwavelength pulse spectrophotometry -In vitro study with a mock circulatory system. |
Abstract | ||
|---|---|---|
Total hemoglobin (tHb), carboxyhemoglobin (COHb), and methemoglobin (MetHb) are usually measured with a CO-oximeter. Noninvasive and continuous measurement of these blood components is expected to decrease the pain of a patient. Therefore, we developed an instrument to measure oxygen saturation (SpO(2), tHb, COHb, and MetHb non invasively. Multiwavelength LED (600, 625, 660, 760, 800, 940, and 1300 nm) and a combined detector (Si, InGaAs) were built into the instrument (Seven wavelengths transparent pulse spectrophotometer). We used the Waseda mock circulatory system, which can simulate blood circulation in tissues and generate a pulse wave mechanically, to estimate the instrument's performance. Furthermore we proposed new calculation formula including DC components of optical density (this method). Under conditions without any change of other components, the mean error +/- standard deviation between this method and the CO-oximetry were SaO(2)=0.0 +/- 1.4%, tHb=0.0 +/- 0.0 g/dl, COHb=0.0 +/- 2.0%, and MetHb=0.0 +/- 0.3%. When the concentration of other components was changed, this method showed mean errors and standard deviations of SaO(2)=0.2 +/- 1.6%, tHb=0.0 +/- 0.4 g/dl, COHb=0.5 +/- 4.1%, and MetHb=0.0 +/- 0.3% |
Year | DOI | Venue |
|---|---|---|
2006 | 10.1109/IEMBS.2006.260273 | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference |
Keywords | DocType | Volume |
oximetry,660 nm,600 nm,multiwavelength led,si,carboxyhemoglobin,940 nm,blood circulation simulation,oxygen saturation measurement,800 nm,proteins,noninvasive measurement,1300 nm,biochemistry,760 nm,molecular biophysics,tissue,total hemoglobin derivatives,spectrophotometry,optical density,methemoglobin,light emitting diodes,co-oximetry,biological tissues,ingaas,multiwavelength pulse spectrophotometry,625 nm,waseda mock circulatory system,haemodynamics,blood,oxygen saturation,mean error,standard deviation | Conference | 1 |
ISSN | ISBN | Citations |
1557-170X | 1-4244-003303 | 0 |
PageRank | References | Authors |
0.34 | 0 | 7 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Hironori Suzaki | 1 | 0 | 0.34 |
| Naoki Kobayashi | 2 | 0 | 0.34 |
| Takashi Nagaoka | 3 | 0 | 0.34 |
| Kiyotaka Iwasaki | 4 | 0 | 0.68 |
| Mitsuo Umezu | 5 | 0 | 0.34 |
| Sunao Takeda | 6 | 0 | 0.34 |
| Tatsuo Togawa | 7 | 0 | 0.34 |