Paper Info
Title
Effects of pressure-dependent segmental arterial compliance and postural changes on pulse wave transmission in an arterial model of the human upper limb.
Abstract
With increasing interest in the effect of postural changes on arterial blood pressure and vascular properties, it is important to understand effects of pressure-dependent arterial compliance. This study investigates effects of pressure-dependent compliance on pulse wave velocity (PWVar), pressure wave shape, and transmission characteristics in an arterial model of the human arm from heart to radial artery from supine to standing. Estimated central pressure waveform was used as the input for the model, calculated using a validated transfer function (SphygmoCor, AtCor Medical) from recorded radial pulses in 10 healthy male subjects (53.8 ± 7.9 years) during 0, 30, 60 and 90 degree head-up tilt. A 5-segment linear model was optimized using estimated central and recorded radial arterial pulse; each segment represented by an equivalent inductance, resistance and capacitance (compliance (C)) Pressure-dependent compliance (C(P)=a · e(b · P) was added to develop a nonlinear model, and the radial pulse calculated. Comparison of the radial pulse calculated by the linear and nonlinear models showed no statistical difference in systolic, diastolic, mean, and pulse pressure in any position of tilt. However, waveform shape was increasingly divergent at higher angles of tilt (RMS error 2.3 ± 1.2 mmHg supine, 6.5 ± 3.0 mmHg standing) as was PWVar (0% increase from supine to standing in the linear model, 16.7% increase in nonlinear model). Fourier analysis demonstrated peak amplitude of transmission being at higher frequencies and phase delay being lower in the nonlinear model relative to the linear model. Pressure-dependent arterial compliance, whilst having no effect on peak values of pressure, has significant effects on waveform shape and transmission speed, especially with a more upright position.
Year
DOI
Venue
2011
10.1109/IEMBS.2011.6091592
EMBC
Keywords
Field
DocType
arterial model,pressure dependent segmental arterial compliance,blood vessels,cardiovascular system,human upper limb,pressure wave shape,arterial blood pressure,human arm,postural change,fourier analysis,radial artery,pulse wave transmission,haemodynamics,shape,transfer functions,mathematical model,estimation,pulse pressure,blood pressure,transfer function,linear model
Biomedical engineering,Anatomy,Pulse pressure,Computer science,Waveform,Pulse wave,Electronic engineering,Pulse wave velocity,Blood pressure,Radial artery,Supine position,Amplitude
Conference
Volume
ISSN
ISBN
2011
1557-170X
978-1-4244-4122-8
Citations 
PageRank 
References 
0
0.34
0
Authors
3
Name
Order
Citations
PageRank
Ke Xu100.68
Mark Butlin236.24
Albert Avolio33216.60