Title
Image processing challenges in the creation of spatiotemporal gene expression atlases of developing embryos.
Abstract
To properly understand and model animal embryogenesis it is crucial to obtain detailed measurements, both in time and space, about their gene expression domains and cell dynamics. Such challenge has been confronted in recent years by a surge of atlases which integrate a statistically relevant number of different individuals to get robust, complete information about their spatiotemporal locations of gene patterns. This paper will discuss the fundamental image analysis strategies required to build such models and the most common problems found along the way. We also discuss the main challenges and future goals in the field.
Year
DOI
Venue
2011
10.1109/IEMBS.2011.6091687
EMBC
Keywords
Field
DocType
gene expression domain,cellular biophysics,image processing,genetics,developing embryos,gene pattern spatiotemporal locations,biological techniques,biology computing,molecular biophysics,spatiotemporal gene expression atlas,cell dynamics,animal embryogenesis,three dimensional,image analysis,gene expression,embryo,embryos,microscopy
Data science,Computer vision,Cellular biophysics,Spatiotemporal gene expression,Computer science,Image processing,Artificial intelligence,Bioinformatics,Complete information
Conference
Volume
ISSN
ISBN
2011
1557-170X
978-1-4244-4122-8
Citations 
PageRank 
References 
0
0.34
6
Authors
10