Paper Info
Title
Stiffness mapping prostate biopsy samples using a tactile sensor.
Abstract
Previous studies have demonstrated that the stiffness of cancerous cells reflects their pathological stage and progression rates, with increased cancerous cell stiffness associated with increased aggressiveness. Therefore, the elasticity of the cancerous cells has the potential to be used as an indicator of the cancer's aggressiveness. However, the sensitivity and resolution of current palpation and imaging techniques are not sufficient to detect small cancerous tissues. In previous studies, we developed a tactile-based device to map with high resolution the stiffness of a tissue section. The purpose of this study is to evaluate this device using different tissues (BPH, Cancer and PZ) collected from human prostates. The preliminary results show that the tactile device is sensitive enough to tell the differences of the stiffness of different tissues. The results also disclosed the factors (humidity, temperature and tissue degradation) which could dramatically affect the results of stiffness mapping. The tactile technology described in this paper has the potential to help disclose the underlying mechanical mechanisms that lead to increased stiffness in prostate tumors.
Year
DOI
Venue
2011
10.1109/IEMBS.2011.6092101
EMBC
Keywords
Field
DocType
biopsy,biomechanics,cellular biophysics,tactile sensor,bph,human prostates,biomedical equipment,pz,cancer,elastic constants,prostate biopsy sample,tactile device,tactile sensors,tumours,prostate tumors,stiffness mapping,temperature measurement,high resolution,imaging
Biomedical engineering,Computer science,Stiffness,Biopsy,Prostate biopsy,Palpation,Prostate cancer,Biomechanics,Cancer,Pathology,Tactile sensor
Conference
Volume
ISSN
ISBN
2011
1557-170X
978-1-4244-4122-8
Citations 
PageRank 
References 
0
0.34
0
Authors
4
Name
Order
Citations
PageRank
Qiyu Peng100.34
Sadao Omata2173.20
Donna M Peehl300.34
Chris E Constantinou400.34