Abstract | ||
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The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models. It is also an information often experimentally available to the biologist. This paper introduces a numerical tool based on the sensitivity analysis of the PRC to adapt initial model parameters in order to match a particular PRC shape. We illustrate the approach on a simple biochemical model of circadian oscillator. |
Year | DOI | Venue |
---|---|---|
2011 | 10.1109/CDC.2011.6161168 | Decision and Control and European Control Conference |
Keywords | Field | DocType |
biology,oscillators,PRC,biochemical model,circadian oscillator,complex oscillator models,initial model parameters,numerical tool,phase response curve,sensitivity analysis | Oscillation,Nonlinear system,Computer science,Control theory,Phase response curve,Circadian clock | Conference |
ISSN | ISBN | Citations |
0743-1546 E-ISBN : 978-1-61284-799-3 | 978-1-61284-799-3 | 0 |
PageRank | References | Authors |
0.34 | 2 | 2 |
Name | Order | Citations | PageRank |
---|---|---|---|
Pierre Sacre | 1 | 12 | 1.21 |
Rodolphe Sepulchre | 2 | 264 | 26.40 |