Title
A closed-loop system for artifact mitigation in ambulatory electrocardiogram monitoring
Abstract
Motion artifacts interfere with electrocardiogram (ECG) detection and information processing. In this paper, we present an independent component analysis based technique to mitigate these signal artifacts. We propose a new statistical measure to enable an automatic identification and removal of independent components, which correspond to the sources of noise. For the first time, we also present a signal-dependent closed-loop system for the quality assessment of the denoised ECG. In one experiment, noisy data is obtained by the addition of calibrated amounts of noise from the MIT-BIH NST database to the AHA ECG database. Arrhythmia classification based on a state-of-the-art algorithm with the direct use of noisy data thus obtained shows sensitivity and positive predictivity values of 87.7% and 90.0%, respectively, at an input signal SNR of -9 dB. Detection with the use of ECG data denoised by the proposed approach exhibits significant improvement in the performance of the classifier with the corresponding results being 96.5% and 99.1%, respectively. In a related lab trial, we demonstrate a reduction in RMS error of instantaneous heart rate estimates from 47.2% to 7.0% with the use of 56 minutes of denoised ECG from four physically active subjects. To validate our experiments, we develop a closed-loop, ambulatory ECG monitoring platform, which consumes 2.17 mW of power and delivers a data rate of 33 kbps over a dedicated UWB link.
Year
DOI
Venue
2012
10.1109/DATE.2012.6176510
Design, Automation & Test in Europe Conference & Exhibition
Keywords
Field
DocType
electrocardiography,feature extraction,independent component analysis,medical disorders,medical signal detection,patient monitoring,signal classification,AHA ECG database,MIT-BIH NST database,ambulatory electrocardiogram monitoring platforms,arrhythmia classification,dedicated UWB link,denoised ECG signal detection,feature extraction,independent component analysis,information processing,motion artifact mitigation,power 2.17 mW,signal-dependent closed-loop system,state-of-the-art algorithm
Noise reduction,Noise measurement,Remote patient monitoring,Computer science,Signal-to-noise ratio,Feature extraction,Real-time computing,Root-mean-square deviation,Independent component analysis,Classifier (linguistics)
Conference
ISSN
ISBN
Citations 
1530-1591
978-1-4577-2145-8
1
PageRank 
References 
Authors
0.41
6
4
Name
Order
Citations
PageRank
Mohammed Shoaib1204.34
Gene Marsh210.41
Harinath Garudadri317123.32
Somdeb Majumdar441.17