Name
Title | ||
|---|---|---|
CHANGES IN ANATOMICAL BRAIN CONNECTIVITY BETWEEN AGES 12 AND 30: A HARDI STUDY OF 467 ADOLESCENTS AND ADULTS. |
Abstract | ||
|---|---|---|
Graph theory can be applied to matrices that represent the brain's anatomical connections, to better understand global properties of anatomical networks, such as their clustering, efficiency and "small-world" topology. Network analysis is popular in adult studies of connectivity, but only one study - in just 30 subjects - has examined how network measures change as the brain develops over this period. Here we assessed the developmental trajectory of graph theory metrics of structural brain connectivity in a cross-sectional study of 467 subjects, aged 12 to 30. We computed network measures from 70×70 connectivity matrices of fiber density generated using whole-brain tractography in 4-Tesla 105-gradient high angular resolution diffusion images (HARDI). We assessed global efficiency and modularity, and both age and age(2) effects were identified. HARDI-based connectivity maps are sensitive to the remodeling and refinement of structural brain connections as the human brain develops. |
Year | DOI | Venue |
|---|---|---|
2012 | 10.1109/ISBI.2012.6235695 | Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging |
Keywords | Field | DocType |
structural connectivity,paediatrics,hardi study,connectivity map,developmental trajectory,tractography,magnetic flux density 4 t,high angular resolution diffusion images,network clustering,adolescents,anatomical networks,biomedical mri,network analyses,anatomical brain connectivity,adults,brain,small-world topology,graph theory,development,network analysis,fiber density,graph theory metrics,neural nets,structural brain connectivity,high angular resolution diffusion imaging (hardi),whole-brain tractography | Graph theory,Neuroscience,Pattern recognition,Human brain,Artificial intelligence,Network analysis,Cluster analysis,Tractography,Modularity,Mathematics | Conference |
ISSN | ISBN | Citations |
1945-7928 | 978-1-4577-1857-1 | 3 |
PageRank | References | Authors |
0.41 | 2 | 10 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Emily L. Dennis | 1 | 3 | 0.41 |
| Jahanshad Neda | 2 | 86 | 6.31 |
| Arthur W Toga | 3 | 791 | 55.66 |
| Kori Johnson | 4 | 3 | 0.41 |
| katie l mcmahon | 5 | 36 | 5.26 |
| Greig I. de Zubicaray | 6 | 16 | 2.84 |
| Nicholas G. Martin | 7 | 16 | 2.98 |
| Ian Hickie | 8 | 57 | 4.95 |
| Margaret J Wright | 9 | 35 | 4.14 |
| Paul M. Thompson | 10 | 18 | 1.90 |