Title
A coupling method for a cardiovascular simulation model which includes the Kalman filter.
Abstract
Multi-scale models of the cardiovascular system provide new insight that was unavailable with in vivo and in vitro experiments. For the cardiovascular system, multi-scale simulations provide a valuable perspective in analyzing the interaction of three phenomenons occurring at different spatial scales: circulatory hemodynamics, ventricular structural dynamics, and myocardial excitation-contraction. In order to simulate these interactions, multiscale cardiovascular simulation systems couple models that simulate different phenomena. However, coupling methods require a significant amount of calculation, since a system of non-linear equations must be solved for each timestep. Therefore, we proposed a coupling method which decreases the amount of calculation by using the Kalman filter. In our method, the Kalman filter calculates approximations for the solution to the system of non-linear equations at each timestep. The approximations are then used as initial values for solving the system of non-linear equations. The proposed method decreases the number of iterations required by 94.0% compared to the conventional strong coupling method. When compared with a smoothing spline predictor, the proposed method required 49.4% fewer iterations.
Year
DOI
Venue
2012
10.1109/EMBC.2012.6346157
EMBC
Keywords
Field
DocType
ventricular structural dynamics,kalman filter,kalman filters,myocardial excitation-contraction,medical signal processing,circulatory hemodynamics,cardiovascular system,physiological models,cardiovascular simulation model,in vitro experiments,in vivo experiments,conventional strong coupling method,spatial scales,smoothing spline predictor,multiscale models,nonlinear equations,haemodynamics
Coupling,Nonlinear system,Control theory,Computer science,Smoothing spline,Kalman filter
Conference
Volume
ISSN
ISBN
2012
1557-170X
978-1-4577-1787-1
Citations 
PageRank 
References 
1
0.42
1
Authors
4
Name
Order
Citations
PageRank
Yuki Hasegawa110.76
Takao Shimayoshi2106.87
Akira Amano3337.69
Tetsuya Matsuda4268.88