Paper Info
Title
On-demand controlled release of anti-inflammatory and analgesic drugs from conducting polymer films to aid in wound healing.
Abstract
An electronically-controlled drug delivery system (eDDS) for the on-demand release of anti-inflammatory, anti-microbial and analgesic agents to aid in wound healing is currently under development. The loading of several drugs into conductive polymer films and their subsequent on-demand, controlled release upon application of an electrical potential to the polymer film has been demonstrated. The loading and release (active and passive) of Ibuprofen sodium salt - a negatively charged analgesic and anti-inflammatory agent - from polypyrrole films is described. Major challenges identified include precise control over drug loading and passive release from the conducting polymers in the absence of an applied potential.
Year
DOI
Venue
2012
10.1109/EMBC.2012.6346153
EMBC
Keywords
Field
DocType
antiinflammatory drugs,electronically-controlled drug delivery system,bioelectric potentials,wound healing,conducting polymer films,biomedical materials,drug loading,ibuprofen sodium salt,wounds,electrical potential,polymer films,analgesic drugs,negatively charged analgesic agent,thin films,antimicrobial agents,drug delivery systems,on-demand controlled release,conducting polymers,polypyrrole films,negatively charged antiinflammatory agent,drugs
Biomedical engineering,Conductive polymer,Polymer,Computer science,Analgesic,Drug delivery,Drug,Controlled release,Polypyrrole,Wound healing
Conference
Volume
ISSN
ISBN
2012
1557-170X
978-1-4577-1787-1
Citations 
PageRank 
References 
0
0.34
0
Authors
8
Name
Order
Citations
PageRank
Gusphyl A Justin111.01
Siqiang Zhu200.34
Theodore R Nicholson300.34
Jeffrey Maskrod400.34
Joseph Mbugua500.34
Mark Chase600.34
June-ho Jung700.34
Ramil Marcelo L Mercado800.34