Title
A framework for myoarchitecture analysis of high resolution cardiac MRI and comparison with diffusion tensor MRI.
Abstract
The ventricular myocardium has a structure of branching laminae through which course regularly orientated myofibers, an architecture important in excitation and contraction. Quantifying this architecture is vital for understanding normal and disease states in the heart and for assessing their impact on electrical function. These data are also highly important in the construction of scientifically and clinically useful computer models of cardiac electrical behavior. Detailed structural information has previously been obtained from serial imaging. In this work we assess the potential for high-resolution (HR) MRI as a means to furnish useful myoarchitecture and compare and contrast this approach with the growing use of DT. Using rat hearts, we conclude that both approaches have strengths and weaknesses, however, HR-MRI may provide a consistently more robust picture of the myoarchitecture in small hearts.
Year
DOI
Venue
2012
10.1109/EMBC.2012.6346859
EMBC
Keywords
Field
DocType
ventricular myocardium,cardiology,diseases,myofiber excitation,regularly orientated myofibers,high resolution cardiac mri,biodiffusion,serial imaging,myofiber contraction,electrical function,diffusion tensor mri,disease states,biomedical mri,bioelectric phenomena,image sequences,cardiac electrical behavior,muscle,myoarchitecture analysis,rat hearts,medical image processing,laminae branching
Biomedical engineering,Diffusion MRI,Computer science,Branching (version control)
Conference
Volume
ISSN
ISBN
2012
1557-170X
978-1-4577-1787-1
Citations 
PageRank 
References 
3
0.58
1
Authors
6
Name
Order
Citations
PageRank
Stephen H. Gilbert1154.55
Greg B. Sands2195.98
Ian J LeGrice341.88
Bruce Smaill463.35
Olivier Bernus575.37
Mark L. Trew63211.43