Title
Estimation of central aortic pressure waveform features derived from the brachial cuff volume displacement waveform.
Abstract
There is increasing interest in non-invasive estimation of central aortic waveform parameters in the clinical setting. However, controversy has arisen around radial tonometric based systems due to the requirement of a trained operator or lack of ease of use, especially in the clinical environment. A recently developed device utilizes a novel algorithm for brachial cuff based assessment of aortic pressure values and waveform (SphygmoCor XCEL, AtCor Medical). The cuff was inflated to 10 mmHg below an individual's diastolic blood pressure and the brachial volume displacement waveform recorded. The aortic waveform was derived using proprietary digital signal processing and transfer function applied to the recorded waveform. The aortic waveform was also estimated using a validated technique (radial tonometry based assessment, SphygmoCor, AtCor Medical). Measurements were taken in triplicate with each device in 30 people (17 female) aged 22 to 79 years of age. An average for each device for each individual was calculated, and the results from the two devices were compared using regression and Bland-Altman analysis. A high correlation was found between the devices for measures of aortic systolic (R(2)=0.99) and diastolic (R(2)=0.98) pressure. Augmentation index and subendocardial viability ratio both had a between device R(2) value of 0.82. The difference between devices for measured aortic systolic pressure was 0.5±1.8 mmHg, and for augmentation index, 1.8±7.0%. The brachial cuff based approach, with an individualized sub-diastolic cuff pressure, provides an operator independent method of assessing not only systolic pressure, but also aortic waveform features, comparable to existing validated tonometric-based methods.
Year
DOI
Venue
2012
10.1109/EMBC.2012.6346494
EMBC
Keywords
Field
DocType
sphygmocor xcel,brachial cuff volume displacement waveform,blood pressure measurement,regression analysis,blood vessels,clinical setting,noninvasive estimation,atcor medical,bland-altman analysis,augmentation index,diastolic blood pressure,proprietary digital signal processing,operator independent method,central aortic pressure waveform feature estimation,transfer function,subendocardial viability ratio,radial tonometric based system
Biomedical engineering,Cuff pressure,Aortic pressure,Cuff,Computer science,Aortic pressure waveform,Diastole,Waveform,Blood pressure
Conference
Volume
ISSN
ISBN
2012
1557-170X
978-1-4577-1787-1
Citations 
PageRank 
References 
1
0.38
0
Authors
3
Name
Order
Citations
PageRank
Mark Butlin136.24
Ahmad Qasem2112.86
Albert Avolio33216.60